Plexaderm VS Genucel (2024 Review) – Which Is The #1?

It’s time to compare 2 of the top products against under-eye aging – Plexaderm VS Genucel.

Both products are very popular – but they also have some questionable aspects.

So here comes the question:

  • Which of them can really help with under-eye problems?
  • Which will give long-term effects?
  • And lastly, which is a better deal overall?

I dug deep into these 2 products, in order to give you the best recommendation (+ video).

Note: This review is based on my experience + research on these 2 products.

Plexaderm Or Genucel? (In A Nutshell)

Honestly, out of these 2 products – Plexaderm is slightly better for several reasons:

  1. Cheaper price
  2. More authentic customer reviews
  3. More buying options (in terms of bundles/packages)
  4. A lot more info available behind

Genucel also has some general info – but it's quite hard to find at first.

Besides, its features are listed in a very confusing manner.

Plexaderm costs around $60, which isn't too affordable.

But even so – it's still cheaper than $89 (which is the price of Genucel).

Now – if you're looking for the best anti-aging product available, I wouldn't recommend any of these 2.

There is another alternative that is way better than both Plexaderm and Genucel.

You can get it for only $60 – and its anti-aging effects is a lot more potent.

But between these 2, my recommendation is probably Plexaderm.




#1 – Ingredients – WINNER: Genucel

In my opinion, Genucel's formula is better compared to Plexaderm:

  • has more ingredients overall
  • contains several vitamins and plant extracts
  • has some major skin care compounds

But I will give you more details about each product's ingredients.

Note: I analyzed the key ingredients of the two skin care products.

1. Plexaderm's Ingredients

Unlike Genucel, Plexaderm has fewer ingredients in its final formula.

Now – among all its compounds, here are the most important ones:

  1. Argireline – lessens the formation of fine lines [1]
  2. Soluble Collagen – acts like a filler for fine lines [2]
  3. Hydrolyzed Rice Protein – maintains skin moisturized [3]

Unfortunately – judging after its ingredients, Plexaderm doesn't seem very potent.

Its overall formula looks more suitable for aesthetic purposes (not for an actual treatment).

That's why the effect tends to lasts quite a short period.

2. Genucel's Ingredients

Again – between the two, Genucel has a more promising formula.

It's not the best anti-aging cream I know, in terms of composition.

But its formula is stronger and more potent than that of Plexaderm:

It contains 4 key ingredients:

  1. Eyeseryl® – reduces fine lines [4]
  2. PhytoCellTec® – deeply protects from sun damage [5]
  3. Malus Domestica – increases skin stem cells vitality [6]
  4. Hydrolyzed (Marine) Collagen – repairs elastin fibers and skin collagen [7]

Now – there are other compounds worth mentioning as well.

But they don't have such high concentrations – so they contributes less to the cream's effect.

Overall – between these two, Genucel's formula has more potential for a long-term effect.


If you compare them side by side – Genucel has a more promising formula.

  • Genucel has a lot more skin care ingredients for the long-term
  • Plexaderm's compounds don't have too many anti-aging benefits

Now, each of these 2 products has a different goal.

So their ingredient have quite a different skin effect as well.

For this reason – if you want a long-term effect, go for Genucel.

But if you want a fast aesthetic effect, choose Plexaderm instead, it's better for the short run.


#2 – Consistency & Dosage – WINNER: Plexaderm

When it comes to directions and consistency, Plexaderm wins this time:

  • has some clearer directions on how to use it
  • its texture is described in details

But let's look further at each product.

1. Plexaderm

Here's what you should know about this cream's texture:

  • a little thick in consistency
  • light to medium beige in color
  • faint chemical scent

For the instructions on how to use it properly, it has quite a few specifications as well:

  1. You have to apply it in upward and outward strokes.
  2. Make sure to wait until it soaks in (10 minutes).
  3. Apply it daily.

Other than that, there are a few tips on what you can combine it with:

  • an oil-free moisturizer (10-20 minutes prior)
  • makeup with dry/powdery formula

So in my view, this cream has a lot more info – which is good for the consumers.

Especially those who want to use the product correctly and properly.

2. Genucel

There isn't much info on how Genucel looks like – but here's what I found out about it:

  • color light to medium beige
  • slightly thick
  • light chemical scent

And for the cream's dosage, you should use it twice a day.

In terms of application – there isn't a very detailed instruction page.

But you can apply it as any regular under-eye cream.

As I said – the instructions are a little off for me, because they could have been better.

It's always good to have a product with clear directions on how to use it.


Even though Plexaderm is more of an asesthetic product, it offers a lot more info about its consistency.

Not to mention the very specific directions on how you should use it.

On the other hand, Genucel has only some very brief instructions.

So for this part, Plexaderm is clearly better.



#3 – Results  WINNER: Plexaderm

In terms of product results, Plexaderm has way more customer reviews than Genucel.

This means that a lot of people actually tried Plexaderm and testified about its effects.

So let's take a look at the results experienced by people who bought these products.

Note: I only analyzed authentic reviews, not promotional or fake ones.

1. Plexaderm

As I told you – Plexaderm has a lot of reviews (both positive and negative).

Let's take a look at the most common opinions of people who tried it:

  1. Most say it works and their fine lines were gone.
  2. Some said that it's really good at quick cover-up and acts as fillers.
  3. There are also a lot of complaints about the pump not working.
  4. A few users experienced receiving a dried-up product or an empty bottle.

Plexaderm has some mixed reviews overall – but that's a sign it was used by lots of people. 

I will always prefer a product with more authentic reviews.

So despite its numerous complaints, it doesn't have a negative feedback overall.

2. Genucel

The only reviews I read about this product are from:

  • its official page
  • 3rd party websites

However – there were quite few opinions overall:

  1. Almost all of the positive comments sound generic.
  2. The format of the reviews is written in a promotional tone.
  3. A lot of the comments said it's effective but are not really specific with the effects.
  4. Lastly – a lot of complaints about payments, subscriptions and unsubscribing.

As for the reviews that were 100% authentic, I could only find some on BBB.

In terms of results, this cream has a limited number of people who actually tried it.

Compared to Plexaderm, there are far less opinions.


Both skin care products have enough negative reviews behind

Still, the complaints on Plexaderm are way more general than for Genucel.

So if I have to choose which one is a little better, it would be Plexaderm.

It has more authentic reviews and there are a lot of real customers who were actually satisfied with it.




#4 – Side Effects  DRAW

As I always say, side effects are quite common in any skin care product.

That's because there isn't a product made for everyone.

And Plexaderm and Genucel are about the same at this chapter.

1. Plexaderm

Plexaderm has a lot of reviews – and these are the most common side effects experienced by people who tried it:

  • skin and eye irritation
  • swelling and burning sensations
  • skin redness/abrasion

These side effects are quite serious, to be honest.

Basically – it means that the serum's composition can be too strong.

So not all people can tolerate the formulation.

2. Genucel

Since there are only limited reviews available for Genucel, it's hard to tell if it can cause side effects.

I only encountered one complaint from a customer (saying that it causes a bad skin reaction).

Still – one complaint is not enough.

But if I were to judge, here are the possible side effects of this product:

  • can be too strong for the skin
  • may not work at all
  • might work well

As I said – this product's formula can be either weak or too harsh.

So it may have a lower rate of side effects than Plexaderm, but that's only because it has few reviews overall.


It's safe to say that you will experience fewer side effects with Genucel.

However – this is only because there are not too many customer's testimonies about this cream.

Plexaderm has several complaints on side effects because there are a lot more people who reviewed it.

For now, it's really hard to judge – since these products don't have the same number of opinions.


#5 – Price  WINNER: Plexaderm

When it comes to this, it is obvious which product is cheaper.

Plexaderm costs less than Genucel – so I think it's a better choice.

Note: I will only analyze the price of the 2 skin care products (without the other products from their range).

1. Plexaderm

Compared to Genucel's offers – Plexaderm has a lot more deals.

But even if I choose it as the winner here, I still consider it very expensive:

  • There's a Trial Pack (6 applications) that costs $14.95
  • A full bottle costs $59.95
  • There's a “Buy 2 Get 1 Free”offer (3 bottles) for $119.90
  • Free shipping is included

The good part with Plexaderm is that you have the choice to go for the Trial Pack first.

This is useful especially if you want to test out the product first.

Other than that, the regular price is still very expensive.

So keep in mind that using this product for the long term can be a hole in your budget.

2. Genucel

To summarize everything – the lowest price I could find for Genucel is $89:

  • that's for one tube
  • it only contains 15 ml (0.5 fl. oz.)
  • there's a 1+1 offer for $133.50
  • offers free shipping

Even with all these deals, I still consider Genucel very expensive.

Besides, once you purchase from this brand, you're automatically placed on auto-shipping.

Now – Genucel has many complaints about unsubscribing and extra charges.

So I would seriously think twice about going for it.


Between the 2, Plexaderm is almost $30 cheaper and has a lot more deals than Genucel.

However – both products are still expensive overall.

If you ask me, I would just recommend a product that costs $60 but work much better.

Given its long-term and skin-deep benefits – it makes a much better investment.




#6 – Pros & Cons

If you're still unsure between Plexaderm and Genucel, I made a little summary for you.

Here are the advantages and disadvantages of each product.

1. Plexaderm


2. Genucel



#7 – My Video Review



My Verdict – Plexaderm Or Genucel?

Short answer: Probably Plexaderm – since it scored better overall:

  • Plexaderm won 3 chapters
  • Genucel won 2 chapters

As you noticed, the difference is pretty minor – so both products have their own advantages.

But in my own opinion, Plexaderm is slightly better.

So if you're wondering which one of these products I would try – it would probably Plexaderm:

  • it's way cheaper than Genucel
  • it has lot of authentic customer reviews
  • it's true to its claims

If you want my honest recommendation, it none of these 2 products (neither Plexaderm nor Genucel).

Instead – I recommend a cream called Kollagen Intensiv from Skinception:

  1. Excellent and strong formula with clinical evidence behind.
  2. It has long-term benefits and a proven effect.
  3. It's very good against wrinkles and fine lines.
  4. Works way better than Plexaderm and Genucel.

Although the price of Kollagen Intensiv is $60, you can get it for about $36 in the best case.

That's a lot less than both Plexaderm and Genucel.

Besides avoiding the payment hassles and high chances of side effects, you will also get a better product.

So overall, that's what I would go for.

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Written by 

Paula has a background in Chemistry and continues to pursue further studies in it. She loves searching for the best products in the market that will give excellent benefits to the human body and share them with you.

Last updated: May 15, 2024

10 thoughts on “Plexaderm VS Genucel (2024 Review) – Which Is The #1?

  1. Nice review of comparison between two anti aging creams. I might take advantage of this article to find a good product for my skin coz it needs a bit more care. I use make-up sometimes and I have pimples and dark spots here and there, so my skin could benefit from these products. However, is this the standard? I think there are still better products than the two. Kudos to the effort of comparing the two but hoping for better contenders 🙂 Thanks, Maja

    1. Hello Maja! I always wear makeup too and it feels really good, right? Unfortunately, some people experience dark spots and pimples after using makeup consecutively. But if you ask me, I would say that it’s always better to invest in skin care products to avoid these things from happening. If you take care of your skin, your makeup will look better. To honestly answer your question, both products are not my standard and I agree that there are better products. You can explore my reviews under the skin and anti-aging categories. I hope you’ll find the product you’ll like.

  2. I’ve used both products and color me surprised that there is a review comparing both products. Well, your evaluation is true enough since it is also what I found before deciding to use and buy this product. However, I still like Genucel more. It was more effective for me.

    1. Hey Dodie! This is Angelica. This two products are famous products so it was interesting to us to see just which product is better than the other. Anyway, the final judgment is ultimately up to you so I’m glad that Genucel works great for you. As they say, you do you. Thanks for sharing your experience with Genucel as well as in reading our review. Take care!

  3. I really like your review about this product! You’ve done well explaining everything, even for old people like me.

  4. I don’t know about Genucel but I would certainly stick with Plexaderm though you think that its inferior than the product you recommend. It is what saved me when I was down on the rocks so I really have faith in it. Anyway, thanks for the review Paula. I was really curious on what people has to say about Plexaderm.


  5. I see the comparison and honestly, both still scare me. I will check on the product you recommend if it really is as you say. Thanks, Paula.

    1. Hi Emilia, I’m Angelica. Thank you for the feedback and sharing your insight. We highly recommend the Kollagen Intensiv product by Skinception because it gets the job done not only just for short term but rather in the long run. In fact, if you combine it with this guide, your visage will improve by leaps and bounds because the steps listed here are proven to be effective. There is nothing wrong with being cautious; better to be safe than sorry. All the best!

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