5 Best Digestive Enzymes Supplements

digestive enzymes best of

Have you been feeling bloated lately?

Do you also find yourself constipated quite often?

These are signs that you might need some digestive enzymes.

Because of this, your body is unable to properly digest all the food.

Luckily, this article brings you the 5 best digestive enzymes supplements!

Note: This ranking takes into account the price/quality, ingredients and results of each product.

1. Vita Balance Digestive Enzymes

1. Producer: Vita Balancedigestive enzymes

2. Main Ingredients:

  • Protein Enzymes
  • Carbohydrate Enzymes
  • Lipase
  • Cellulase

3. Best For: Maintaining your digestion in good health.

By doing this, it will also help with the following:

  • enhancing the process of digestion
  • nutrients absorption
  • reduced bloating and overall discomfort

4. Standard VS Lowest Price: $24 VS $16 (for largest amount)

Let's start with the best product in this category.

In terms of how it works, this supplement is very straightforward:

  • increases the number of enzymes in your stomach
  • makes food easier to break down
  • speeds up the absorption process

The fact that this sounds so simple makes it all the more appealing.

Digestive Enzymes2

In fact, this is how most digestive supplements claim to help you.

So this mechanism of action is very effective.

What makes this specific product special is the formula:

  • varied types of enzymes
  • they help you digest all sorts of food
  • each brings different benefits to the mix

Overall, this unique blend of enzymes ensures that you get every advantage this supplement offers.

digestive enzymes3

To seal the deal, there are no risks involved in terms of adverse reactions.

Generally, digestive supplements rarely cause side effects.

So there is no need to worry about that.

Plus, the quality is very high for the price it demands.

In fact, this product has the best formula out of all supplements of this kind.

Plus, for such a low price, you really cannot pass it up.

See my full Vita Balance Digestive Enzymes review

  • Excellent mix of digestive enzymes
  • Contains the most important enzymes
  • Manageable serving size
  • Effective against most digestive issues
  • Many positive user experiences
  • Very affordable
  • Safe formula
  • Is not shipped worldwide
  • Has shipping fees
  • Only sold on its official website




2. Enzyme MD

1. Producer: 1MDenzmd

2. Main Ingredients:

  • Saccharomyces boulardii
  • Alpha-amylase
  • Bromelain
  • Peptidase

3. Best For: Supporting a healthy digestion.

It does so by:

  • enhancing the absorption of nutrients
  • getting rid of gases
  • diminishing indigestion

4. Standard VS Lowest Price: $43 VS $26 (largest supply + subscription)

This supplement is amazing as an alternative to my #1 recommendation.

That's because this product is intended to work as an all-rounder in terms of digestion:

  • purifies your body of toxins
  • helps with indigestion
  • promotes a healthy digestion
  • boosts the absorption of nutrients
  • eliminates gases

The fact that it's so versatile makes it a very great choice.


In fact, this product is filled with enzymes, which makes it all the more useful.

Plus, the overall dose of ingredients is quite high.

So you know this is a potent product, which is very helpful.

That tells you that it's going to work.

What's more – it has a 90-day money back guarantee, which is awesome:

  • very generous for a digestive supplement
  • shows that this product does not get returned often

Despite the fact that it's pricier than my top pick…

Its flexibility is very worth it if you're looking to improve your digestion.

See my full Enzyme MD review

  • Amazing blend of digestive enzymes
  • Consists of important enzymes
  • Very versatile
  • Many pleased customers
  • Good serving size
  • 90-day money back guarantee
  • Rather pricy
  • Original product is only on official website
  • Mild risk of side effects




3. Zenwise Digestive Enzymes

1. Producer: Zenwise

2. Main Ingredients: 

  • Advanced Enzyme & Prebiotic System
  • Probiotic Blend
  • Sea Vegetable Complex
  • Herbal Compounds 

3. Best For: Maintains the health of your digestion.

It works by:

  • promoting immunity
  • taking care of stomach discomfort
  • providing enzymes

4. Standard VS Lowest Price: Starts at $19.97

Much like previous products from this list, this one improves digestion by:

  • supporting your immune system
  • maintaining gut microbiota
  • aids in food digestion
  • provides antioxidants
  • helps with nutrient absorption
  • alleviates gas, constipation & overall discomfort

By honoring all these promises, Zenwise Digestive Enzymes keeps your digestion intact.

As a bonus, it also comes with a prebiotic & probiotic blend.

This helps to further balance the well-being of your digestive system [1].

The formula does not have high doses, but that's for the better.

This is not supposed to be a strong supplement, so make note of that.

Another convenient aspect is that it only requires you to take 1 pill per day.

Taking into account that you pay about $20 for a 2-month supply…

That's pretty good!

However, be aware that this product may come with side effects.

Specifically, the Sea Vegetable Complex may trigger stomach cramps.

But if that's not an issue for you, this product will work just fine for you!

See my full Zenwise Digestive Enzymes review

  • Great for improving digestion
  • Good formula
  • Low serving size (1 pill per day)
  • Quite affordable
  • Many positive user experiences
  • Money-back guarantee
  • Higher rate of side effects (than other products)
  • Several complaints about shipping



4. FodMate

1. Producer: Microbiome Labsfodmate

2. Main Ingredients:

  • Lactase
  • Alpha-Galactosidase
  • Glucose isomerase

3. Best For: Promoting digestive health.

It does so by feeding the microbiome in your gut.

4. Standard VS Lowest Price: $60 (no discount for larger quantities)

In short, this supplement aids your digestion by doing the following:

  • breaks down fibers that are difficult to assimilate [2]
  • provides beneficial bacteria if they are lacking
  • preserve the harmony in your digestive tract

Essentially, this product promises to solve your digestive issues…

While giving your diet as much freedom as possible.


The prime attraction of this supplement is the convenience factor.

Without making a single change in your diet, this supplement can take care of your digestion.

However, there are also a few downsides:

  • not exactly affordable
  • high serving size

On top of the fact that it doesn't have a modest price tag…

It also requires you to take 2 pills at once, 2-3 times a day.

That's potentially 6 capsules a day, which is quite a lot.

So you make the call on whether that's worth it or not.

If you prefer higher quality at a lower price point, feel free to go for my top pick.

Regardless, this is still a great choice.

  • Good for maintaining your digestion
  • Great formula
  • Lets you consume foods rich in fiber with no drawbacks
  • Regulates bowel movement
  • High serving size
  • Rather pricy



5. Digestive Enzymes Ultra

1. Producer: Pure Encapsulations digestive enzymes ultra

2. Main Ingredients:

  • Lipase
  • Amylase
  • Protease

3. Best For: Supports a healthy digestive tract.

4. Standard VS Lowest Price: Around $60 (no discount)

This supplement brings all sorts of vegetarian enzymes to aid your digestion:

  • some enzymes are not produced in your body [3]
  • they break down nutrients
  • this makes them easier to absorb

By providing you with enzymes ready to process any food…

In ensures that your digestion remains safe.

digestive enzymes ultra2

The serving size is quite nice, as it's only 2 capsules per day.

Plus, there are no side effects to be concerned about.

So it's a pretty safe option to try, aside from its price tag.

This digestive product will surely help with your issue, but if you want something better…

Please check my top recommendations from this list.

  • Good for managing digestive health
  • Provides enzymes that are not found in your body naturally
  • Helps digest all types of nutrients
  • Safe formula
  • Quite a high price point
  • Not that many user reviews available



My Verdict – What Is The Best Digestive Enzymes Supplement?

Short answer: Vita Balance Digestive Enzymes, of course!

It's the best product from this list by a long shot:digestive enzymes

  • First-rate blend of digestive enzymes
  • Contains the most important enzymes
  • Combats most digestive concerns
  • Convenient serving size
  • Doesn't break the bank
  • No risk of side effects
  • Lots of satisfied customers

In other words, if there is one product that can relieve all your digestive issues…

It's surely Vita Balance Digestive Enzymes!

Of course, there are lots of options when it comes to digestive supplements.

But when looking at price/quality ratio, ingredients and overall effectiveness…

This one wins by a mile.

So you can be sure that it won't disappoint you.




1 – https://www.eufic.org/article/probiotics-and-prebiotics

2 – https://www.ncbi.nlm.nih.gov/pmc/-articles/PMC4923703/

3 – https://www.hopkinsmedicine.org/-health/digestive-enzymes

Written by 

Sara is passionate about health, beauty and cosmetics. She likes to do research and to find new information about various medical topics. You can connect with her via Linkedin.

Last updated: February 16, 2023

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